Bird flu still a menace in Asia and beyond

HANOI, Vietnam (AP) — Thought bird flu was gone? Recent human deaths in Asia and Egypt are a reminder that the H5N1 virus is still alive and dangerous, and Vietnam is grappling with a new strain that has outsmarted vaccines used to protect poultry flocks.

Ten people have died in Cambodia, Indonesia, Egypt, China and Vietnam since December during the prime-time flu season when the virus typically flares in poultry.

"We are worried, and we will be very cautious," said To Long Thanh, director of Vietnam's Center for Animal Health Diagnostics in Vietnam.

The H5N1 virus has killed 345 people worldwide since 2003, when it rampaged across large swaths of Asia decimating poultry stocks before later surfacing in parts of Africa, the Middle East and Europe. The number of poultry outbreaks has greatly diminished since then, but the virus remains entrenched in several countries and continues to surface sporadically, resulting in 20 to 30 human deaths globally in recent years.

Bird flu remains hard for people to catch, with most people sickened after being in close contact with infected poultry, but experts have long feared it could spark a pandemic if it mutates into a form that spreads easily among people.

The fresh wave of cases comes amid a controversy involving scientists who created new lab-only versions of the virus that spread more easily among animals, hoping to better understand it. After a loud uproar over whether publishing the research would put the recipe for a bioweapon into the hands of terrorists, the researchers have agreed to temporarily halt their work.

They are set to wrap up a two-day meeting on the issue Friday with international experts at the World Health Organization in Geneva.

After the meeting, WHO spokesman Gregory Hartl told The Associated Press the work would not be published until a full discussion could be held about both the risks and benefits of the research and risks of the virus itself. He said the consensus among experts voiced by a lead researcher was that the work should be published eventually since there was only a small chance the virus could be used as a bioweapon.

Vietnam has long struggled to control the virus, but it has made progress — going 21 months before reporting its two most recent deaths in the past month. It has also experienced a burst of poultry outbreaks in 11 provinces nationwide over the same period. Officials have issued fresh warnings for farmers to beef up surveillance, especially since they can no longer rely on the latest poultry vaccine in the north and central areas where it is weak or useless against a new strain that has emerged in the region.

"We have to increase biosecurity," said Thanh, the animal diagnostics director.

The new strain had earlier been identified in China and was also recently found in Bangladesh and Nepal, where it likely spread via wild birds, said Jan Slingenbergh, a senior animal health officer at the U.N. Food and Agriculture Organization in Rome.

Viruses are constantly mutating and require new vaccines to protect against infection — the same reason new human seasonal flu shots are developed each year. A new vaccine is in the works, and scientists have stressed that the new strain has not changed in any way that suggests the virus is becoming more dangerous.

The U.N. agriculture agency warned of a possible resurgence in bird flu outbreaks after the new strain was identified, potentially increasing risk to humans. However, Vietnam's two recent deaths occurred in the southern Mekong Delta, where the vaccine remains effective. WHO stressed it is also normal to see a spike in cases and poultry outbreaks during this time of year.

"WHO has always said that as long as the virus is entrenched in poultry, which it is, there continues to be the risk of bird-to-human transmission," spokesman Hartl said in Geneva. "That risk means that you cannot predict exactly if the transmission will happen and if it will be regular, but there is the risk so that's why it's not surprising to see cases."

Vietnam buys most of its poultry vaccine from China, which has continued with its robust vaccination campaign of some 15 billion doses despite the emergence of the new strain. Researchers there have developed a new version that works against the strain, but it's unclear when it might be ready for distribution, said Keith Hamilton, an animal influenza expert at the Paris-based World Organization of Animal Health.

"We emphasize that vaccination is a complementary tool," he said. "It has to be used in conjunction with other control measures — biosecurity on farms, early detection is essential, so is a rapid response to contain and eliminate sources of disease."

But in Ha Nam province, on the outskirts of Vietnam's capital, Hanoi, animal health officials are desperate to contain a poultry outbreak that hit last week. They have ordered 1 million doses of vaccine, hoping it will provide at least some protection.

"I wish to have an effective vaccine against bird flu as soon as possible, so I can go on raising ducks," said farmer Nguyen Van Duong, whose entire flock was slaughtered after the virus was detected.

"I am devastated at losing my investment on the ducks, but we will do anything to work with the authorities to stop it from spreading. The last thing we want is an outbreak to happen again."

____

Follow Asia-Pacific Medical Writer Margie Mason at www.twitter.com/margiemasonap

View the original article here

Bird flu still a menace in Asia and beyond

HANOI, Vietnam (AP) — Thought bird flu was gone? Recent human deaths in Asia and Egypt are a reminder that the H5N1 virus is still alive and dangerous, and Vietnam is grappling with a new strain that has outsmarted vaccines used to protect poultry flocks.

Ten people have died in Cambodia, Indonesia, Egypt, China and Vietnam since December during the prime-time flu season when the virus typically flares in poultry.

"We are worried, and we will be very cautious," said To Long Thanh, director of Vietnam's Center for Animal Health Diagnostics in Vietnam.

The H5N1 virus has killed 345 people worldwide since 2003, when it rampaged across large swaths of Asia decimating poultry stocks before later surfacing in parts of Africa, the Middle East and Europe. The number of poultry outbreaks has greatly diminished since then, but the virus remains entrenched in several countries and continues to surface sporadically, resulting in 20 to 30 human deaths globally in recent years.

Bird flu remains hard for people to catch, with most people sickened after being in close contact with infected poultry, but experts have long feared it could spark a pandemic if it mutates into a form that spreads easily among people.

The fresh wave of cases comes amid a controversy involving scientists who created new lab-only versions of the virus that spread more easily among animals, hoping to better understand it. After a loud uproar over whether publishing the research would put the recipe for a bioweapon into the hands of terrorists, the researchers have agreed to temporarily halt their work.

They are set to wrap up a two-day meeting on the issue Friday with international experts at the World Health Organization in Geneva.

After the meeting, WHO spokesman Gregory Hartl told The Associated Press the work would not be published until a full discussion could be held about both the risks and benefits of the research and risks of the virus itself. He said the consensus among experts voiced by a lead researcher was that the work should be published eventually since there was only a small chance the virus could be used as a bioweapon.

Vietnam has long struggled to control the virus, but it has made progress — going 21 months before reporting its two most recent deaths in the past month. It has also experienced a burst of poultry outbreaks in 11 provinces nationwide over the same period. Officials have issued fresh warnings for farmers to beef up surveillance, especially since they can no longer rely on the latest poultry vaccine in the north and central areas where it is weak or useless against a new strain that has emerged in the region.

"We have to increase biosecurity," said Thanh, the animal diagnostics director.

The new strain had earlier been identified in China and was also recently found in Bangladesh and Nepal, where it likely spread via wild birds, said Jan Slingenbergh, a senior animal health officer at the U.N. Food and Agriculture Organization in Rome.

Viruses are constantly mutating and require new vaccines to protect against infection — the same reason new human seasonal flu shots are developed each year. A new vaccine is in the works, and scientists have stressed that the new strain has not changed in any way that suggests the virus is becoming more dangerous.

The U.N. agriculture agency warned of a possible resurgence in bird flu outbreaks after the new strain was identified, potentially increasing risk to humans. However, Vietnam's two recent deaths occurred in the southern Mekong Delta, where the vaccine remains effective. WHO stressed it is also normal to see a spike in cases and poultry outbreaks during this time of year.

"WHO has always said that as long as the virus is entrenched in poultry, which it is, there continues to be the risk of bird-to-human transmission," spokesman Hartl said in Geneva. "That risk means that you cannot predict exactly if the transmission will happen and if it will be regular, but there is the risk so that's why it's not surprising to see cases."

Vietnam buys most of its poultry vaccine from China, which has continued with its robust vaccination campaign of some 15 billion doses despite the emergence of the new strain. Researchers there have developed a new version that works against the strain, but it's unclear when it might be ready for distribution, said Keith Hamilton, an animal influenza expert at the Paris-based World Organization of Animal Health.

"We emphasize that vaccination is a complementary tool," he said. "It has to be used in conjunction with other control measures — biosecurity on farms, early detection is essential, so is a rapid response to contain and eliminate sources of disease."

But in Ha Nam province, on the outskirts of Vietnam's capital, Hanoi, animal health officials are desperate to contain a poultry outbreak that hit last week. They have ordered 1 million doses of vaccine, hoping it will provide at least some protection.

"I wish to have an effective vaccine against bird flu as soon as possible, so I can go on raising ducks," said farmer Nguyen Van Duong, whose entire flock was slaughtered after the virus was detected.

"I am devastated at losing my investment on the ducks, but we will do anything to work with the authorities to stop it from spreading. The last thing we want is an outbreak to happen again."

____

Follow Asia-Pacific Medical Writer Margie Mason at www.twitter.com/margiemasonap

View the original article here

Willie Brown Still a San Francisco Force

“It’s a gorgeous color,” says Willie Brown, the former mayor of San Francisco and Mr. Bashford’s customer and close friend of 45 years. “I wouldn’t even call that burgundy. It’s headed for ... It’s Bordeaux.”

“The color is the reason I brought them over,” Mr. Bashford says. “I wouldn’t push shoes at lunch otherwise.”

“Wilkes, that’s the most sensitive thing you’ve ever said,” Mr. Brown quips.

As repartee, it is pure Willie Lewis Brown Jr., perfected over the four decades he has been a central figure in the city’s political and social life, and served up for almost that long at Le Central, where Mr. Brown, Mr. Bashford and a select group of others — Herb Caen, the San Francisco Chronicle columnist who died in 1997, was a founding member — have assembled every Friday since 1973 to talk politics, restaurants, real estate, children, grandchildren and the occasional pair of shoes.

The lunches are mentioned frequently in Mr. Brown’s own Chronicle column, Willie’s World. And in their way, the gatherings capture the qualities that have made him so lastingly compelling to both his fans and critics — his mischievous wit and infectious charm, his entrancement with power and celebrity, his fondness for $5,000 suits and $2,000 shoes, his loyalty and, at times, imperiousness on full display.

He is 77, 78 next month, and his eyesight has been diminished by retinitis pigmentosa. The political world in which he came of age as a Democrat in the State Assembly — a world of cross-the-aisle compromise and quid pro quo — has given way to Tea Party zeal and ideological intransigence.

But he has refused to creep quietly offstage. Since leaving public office in 2004 at the end of his second term as mayor — the worst day of his career, he says, because “that was my life, my whole life, my first, second and third in my life” — he has remained a power broker, his influence still palpable.

His law firm represents prominent clients, among them Aecom, an engineering firm involved in San Francisco’s central subway project, and the California Online Poker Association. And he offers informal counsel to a stream of business executives, elected officials, and bureaucrats who breakfast with him at the St. Regis, where his apartment is on the 35th floor.

“There are so few people left around with institutional memory, and with a track record that makes that memory advisable,” he said in a recent interview. “I think that’s where I am, that’s who I am and that’s what I do.”

Along with Rose Pak, the Chinese-American community’s powerful organizer, and others, Mr. Brown helped usher Mayor Ed Lee into office in November. A pre-inaugural bash for 400 guests that he hosted at the Palace Hotel’s Garden Court in January was, in contrast to most of Mr. Brown’s parties, not a black-tie affair; to spare Mr. Lee from having to rent a tuxedo, he said.

He rises each morning at 5:30 and forces himself to go to the gym — “If I feel any little tweak anywhere, I stop,” he said.

He follows politics assiduously. He gets along well with Gov. Jerry Brown, as he did with his Republican predecessor, Arnold Schwarzenegger, and retains strong ties to Senator Dianne Feinstein. The Republican presidential race inspires him to punditry (On Mitt Romney: “If Newt Gingrich really wants to get under Romney’s skin, he ought to start calling him by his first name: Willard”; On Newt Gingrich: “Extremely bright, volatile, opinionated”; On Rick Santorum: “a total and complete misfit for elective office”; On Ron Paul: “He is probably the most honest”).

Yet, Mr. Brown laments the intolerance that now dominates Washington and Sacramento.

“Representative democracy is handicapped by preconditions,” he said. “The system now, the participants, are all geared to whether or not their side wins, not whether or not their side is best for the system. That’s a dramatic change from my day.”

Voters, he noted in his 2008 autobiography, “Basic Brown,” wanted “politicians who could make things work and who could work with each other.”

View the original article here